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IgG4-related ophthalmic disease (IgG4-ROD) is the recommended term to describe orbital manifestations of the systemic condition IgG4-related disease,〔 which is characterised by lymphoplasmacytic infiltration, follicle formation and fibrosclerosis of involved structures. It can involve one or more of the orbital structures. Frequently involved structures include the lacrimal glands, extraocular muscles, infraorbital nerve, supraorbital nerve and eyelids.〔〔〔〔〔〔 A prompt response to steroid therapy is a characteristic feature of IgG4-ROD in most cases, as it is with other manifestations of IgG4-related disease, unless significant fibrosis has already occurred.〔〔 ==Nomenclature== Although IgG4-related ophthalmic disease is the recommended name for all orbital manifestations of IgG4-related disease, more precise terminology for the various anatomical variations of the condition can be used. This includes:〔〔 * IgG4-related dacryoadenitis (lacrimal glands) * IgG4-related dacryocystitis (lacrimal sac) * IgG4-related orbital myositis (extraocular muscles) * IgG4-related orbital nerve lesions * IgG4-related optic neuropathy (optic nerve) * IgG4-related orbital inflammation (orbital soft tissue) * IgG4-related pan-orbital inflammation (all of the various types of orbital structures) Names previously used in the diagnosis of cases now considered to be IgG4-ROD have included idiopathic orbital inflammatory disease and orbital pseudotumor.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「IgG4-related ophthalmic disease」の詳細全文を読む スポンサード リンク
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